The Pittsburgh Panthers are 3-1 both straight up and against the spread in their four meetings with Virginia Tech since the teams renewed their rivalry back in 2012. In a big game in the ACC's Coastal Division, Pitt hosts the Hokies on Thursday night at Heinz Field.

Point spread: The Hokies opened as four-point favorites, according to sportsbooks monitored by Odds Shark (line updates and matchup report).

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