The Pittsburgh Panthers are just 1-6 against the spread over their past seven home games, while the Penn State Nittany Lions are 0-9 ATS over their past nine games on the road. How will the spread shake out when Pitt and Penn State renew their great old Keystone State football rivalry Saturday afternoon at Heinz Field?

Point spread: Panthers opened as 4.5-point favorites, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)

College football pick, via Odds Sha...

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