Michigan holds a firm upper hand in the rivalry with Illinois, winning 69 of 94 meetings all time and going 9-2 straight up, although just 6-5 against the spread over the last 11 matchups. The Wolverines look to continue that dominance when they host the Illini on Saturday afternoon at the Big House.

Point spread: The Wolverines opened as 28-point favorites, according to sportsbooks monitored by Odds Shark.

College football pick, via Odds Shark computer: Bleacher Report - College Football
Article is property of BleacherReport.com