Since playing in the national championship game four seasons ago, Notre Dame is just 18-15 straight up against major-conference competition. Some might argue otherwise, but Syracuse qualifies as a major-conference team. How will the Irish fare when they roll with the Orange on Saturday afternoon on a neutral field at MetLife Stadium in New Jersey?

Point spread: The Fighting Irish opened as 12-point favorites, according to sportsbooks monitored by Odds Shark Bleacher Report - College Football
Article is property of BleacherReport.com